intra‐coronary mononuclear bone marrow cell transplantation or intra‐coronary administration of cardiosphere‐derived cells experimental and investigational for members with myocardial infarction
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چکیده
II. Aetna considers autologous intra‐coronary mononuclear bone marrow cell transplantation or intra‐coronary administration of cardiosphere‐derived cells experimental and investigational for members with myocardial infarction and for all other cardiac diseases (e.g., chronic heart failure) because its effectiveness for these indications has not been established. Last Review 06/23/2016 Effective: 03/12/2002 Next Review: 06/22/2017
منابع مشابه
Intra-coronary bone marrow mononuclear cell transplantation in patients with ST-elevation myocardial infarction: a randomized controlled study.
BACKGROUND Stem cell transplantation is a potential treatment to improve left ventricular ejection fraction (LVEF) after ST elevation myocardial infarction (STEMI). However, the outcomes still are controversial. OBJECTIVE To determine the 6-month LVEF of the patients who underwent intra-coronary bone marrow mononuclear cell (BMC) transplantation in patients with STEMI compared with controlled...
متن کاملThe REPAIR-AMI and ASTAMI trials: cell isolation procedures.
10 The time between myocar-dial infarction and intracoronary infusion therapy was nearly identical in the BMC and placebo group (median of 4 days), thus any spontaneous improvement in left ventri-cular ejection fraction (LVEF) prior to intra-coronary infusion therapy may have occurred to the same extent in both groups. As suggested by Marenzi and Bartor-elli, we re-analysed a potential effect o...
متن کاملBone marrow-derived cell transplantation for acute myocardial ischemia.
Acute Myocardial Ischemia To the Editor: We read with interest the report on transcatheter intracoronary transplantation of autologous mononuclear bone marrow-derived cell transplantation by Strauer et al,1 which is a timely addition to the literature of cell transplantation for myocardial repair. From our own experience of bone marrow transplantation into the myocardium of patients undergoing ...
متن کاملRepair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans.
BACKGROUND Experimental data suggest that bone marrow-derived cells may contribute to the healing of myocardial infarction (MI). For this reason, we analyzed 10 patients who were treated by intracoronary transplantation of autologous, mononuclear bone marrow cells (BMCs) in addition to standard therapy after MI. METHODS AND RESULTS After standard therapy for acute MI, 10 patients were transpl...
متن کاملRegeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease: the IACT Study.
OBJECTIVES Stem cell therapy may be useful in chronic myocardial infarction (MI); this is conceivable, but not yet demonstrated in humans. BACKGROUND After acute MI, bone marrow-derived cells improve cardiac function. METHODS We treated 18 consecutive patients with chronic MI (5 months to 8.5 years old) by the intracoronary transplantation of autologous bone marrow mononuclear cells and com...
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